CHRONIC STRESS AND DEPRESSION IN PATIENTS RHEUMATOID ARTHRITIS
Keywords:
autoimmune rheumatic disease, systemic damage, physical discomfortAbstract
Rheumatoid arthritis (RA) is an autoimmune rheumatic disease of unknown etiology that affects 0.5–2% of the adult population at the most working age of 35-55 years and is characterized by chronic erosive arthritis and systemic damage to internal organs. The chronic progressive course of the disease and the accompanying lifelong therapy are accompanied by the development of often irreversible complications and side effects, manifested in changes in appearance, sleep disorders, emotional lability, physical discomfort and significant limitation of functionality. Back in 1961, P.Kielholz He noted the importance of physical and psychological maladaptation and a marked decrease in activity in RA in the development of chronic depression, as well as in the formation of a "vicious circle" of mental and somatic sufferin. Characterological features allow some patients to calmly adapt to new living conditions, while others develop psychopathological conditions that require psychological and medical correction.
References
1.Ravshanova, M., Ibragimov, K., Uralov, R., Xasanov, F., Islamova, K., Abdushukurova, K., ... & Axmedov, I. (2024). Clinical and Immunological Characteristics of Patients with Rheumatoid Arthritis on Synthetic DMARDS Therapy. Frontiers of Global Science, 2(1), 41-47.
2.Ibragimov, K., Sultonov, I., & Ravshanova, M. (2024). The Effectiveness of the Combination Therapy with biologic DMARDS in Rheumatoid Arthritis. Frontiers of Global Science, 2(1), 17-24.
3.Ziyadullaev, S. K., Sultonov, I. I., Dushanova, G. A., & Akbarovna, K. S. (2021). The Effectiveness Of Pharmacotherapy For Dmards With Ra Depending On The C3435t Polymorphism Of The Mdr1 Gene. Int. J. of Aquatic Science, 12(3), 2908-2916.
4.Sobirov, A., & Sultonov, I. (2024). COMPREHENSIVE ANALYSIS OF CLINICAL NEUROPSYCHOLOGICAL AND NEUROIMAGING ASPECTS OF ALZHEIMER'S DISEASE. Frontiers of Global Science, 2(1), 25-29.
5.Islomovich, S. I. (2024). FEATURES OF THE COURSE OF PREGNANCY IN RHEUMATOID ARTHRITIS. International journal of medical sciences, 4(10), 77-84.
6.Islomovich, S. I. (2024). Gender characteristics of the current rheumatoid arthritis. International journal of medical sciences, 4(10), 3-8.
7.Khasan, I., Ibrat, A., Islomovich, S. I., Sukhrobovna, R. M., & Shuxrat, Z. The Association Between Cardiovascular Disease and Conventional DMARDs in Patients with Rheumatoid Arthritis. International journal of health sciences, 6(S8), 5053-5059.
8.Тоиров, Э. С., Ахмедов, И. А., & Султонов, И. И. (2020). Дисбаланс неврной и эндокринной системы при ревматоидном артрите. Journal of cardiorespiratory research, 1(2), 73-76.
9.Хамраева, Н. А., Султонов, И. И., & Хасанов, Ф. Ш. У. (2019). Кожные проявления у больных системной красной волчанкой. Вопросы науки и образования, (28 (77)), 128-131.
10.Sultonov, I. I., Kh, Z. S., Ruzybakieva, M. R., Kireev, V. V., Aripova, T. U., & Suyarov, A. A. (2021). Pharmacogenetic Aspects of Drug Resistance in Rheumatoid Arthritis. Annals of the Romanian Society for Cell Biology, 25(3), 4147-4150.
11.Тоиров, А. Э., Султонов, И. И., & Тоиров, Э. С. (2020). ЗНАЧЕНИЕ ДИСФУНКЦИИ ПОЧЕК У БОЛЬНЫХ ОСТРЫМ ИНФАРКТОМ МИОКАРДА НА ФОНЕ САХАРНОГО ДИАБЕТА 2-ГО ТИПА. Вестник науки и образования, (9-3 (87)), 86-91.
12.Kireev, V. V., Sultonov, I. I., Ziyadulaaev, S. K., Suyarov, A. A., Aripova, T. U., Usmanbekova, K. T., & Nasretdinova, M. T. (2021). Genetic Engineered Preparations-An Innovative Approach in the Treatment of Rheumatoid Arthritis. Annals of the Romanian Society for Cell Biology, 25(3), 4114-4119.
13.Hamraeva, N. A., Sultonov, I. I., & Hasanov, F. S. (2020). Systemic lupus erythematosus treatment strategy. Journal of Critical Reviews, 7(9), 269-270.
14.Иргашева, У. З., Султонов, И. И., & Тоиров, Д. Р. (2013). Признаки дебюта системной красной волчанки. Академический журнал Западной Сибири, 9(1), 15-15.
