JISMONIY FAOLIYAT VA REVMATOID ARTRIT: TADQIQOTLAR VA AMALIYOTLAR TAHLILI
Fargʻona Jamoat Salomatligi Tibbiyot Instituti “Gospital terapiya (labaratoriya)” kafedrasi, t.f.n., Mahmudov Nurillo Ismoilovich taqrizi ostida
Keywords:
revmatoid artrit, yurak-qon tomir kasalliklari, jismoniy faollik, DAS28, sNOS, VAS, autoimmun kasallik.Abstract
Revmatoid artrit (RA) - bu yurak-qon tomir kasalliklarining xavfini oshiradigan eng keng tarqalgan surunkali yallig'lanishli revmatizm kasalligi.[7] Umumiy aholi orasida revmatoid artritning tarqalishi 0.5% dan 1% gacha bo'lishi mumkin. Biroq, ayrim mamlakatlarda bu ko'rsatkich 2% gacha yetishi mumkin. Jahon sog'liqni saqlash tashkiloti (WHO) va boshqa sog'liqni saqlash tashkilotlari tomonidan olib borilgan tadqiqotlar shuni ko'rsatadiki, revmatoid artrit dunyo bo'ylab millionlab odamlarni ta'sir qiladi. Masalan, 2010 yilda o'tkazilgan bir tadqiqotda, dunyo bo'yicha 23.7 million odam revmatoid artritdan aziyat chekkanligi aniqlangan. Har yili yangi revmatoid artrit holatlari soni 100,000 aholiga 20-50 yangi holatni tashkil etishi mumkin.[8] Jahon Sog'liqni Saqlash Tashkiloti (WHO) umumiy aholi o’rtasida yurak-qon tomir kasalliklari xavfini kamaytirish uchun kerak bo'lgan jismoniy faoliyat (JF) turiga oid maxsus tavsiyalarni taklif qiladi. Lekin revmatoid artrit bemorlarida jismoniy faoliyatning yurak-qon tomir xavfini kamaytirishdagi o'rni yetarlicha takidlanmagan.[11] Ushbu maqola RA bilan og'rigan bemorlar uchun jismoniy faoliyatning foydalari va tavsiyalarini ko'rib chiqadi. Maqolada jismoniy faoliyatning turli turlari, ularning RA bilan og'rigan bemorlar uchun qanday foydali ekanligi va jismoniy faoliyat dasturlarini qanday tuzish kerakligi haqida batafsil ma'lumot beriladi.
References
1.Physical Activity in the Management of Rheumatoid Arthritis //Rheumatology International// M. Baillet, J. Zeboulon-Ktorza, C. Gossec, F. Dougados// 2020.
2.Physical Exercise in Patients with Rheumatoid Arthritis: Systematic Review //Brazilian Journal of Rheumatology// M. Di Renzo, M. N. Glace, P. Ricciardi// 2021.
3.Exercise Therapy in Rheumatoid Arthritis: Effects on the Disease Process// Arthritis Research & Therapy// K. L. Stenström, A. Minor// 2013.
4.Benefits of Physical Activity in Patients with Rheumatoid Arthritis //The Journal of Rheumatology// L. Sveaas, M. Smedslund, K. Hagen// 2017.
5.Brown, P., Pratt, A. G., & Hyrich, K. L. (2024). Therapeutic advances in rheumatoid arthritis. The BMJ. Retrieved from https://www.bmj.com/content/384/bmj-2022-070856
6.Babaahmadi, M., Tayebi, B., Gholipour, N. M., Kamardi, M. T., Heidari, S., Baharvand, H., Eslaminejad, M. B., Hajizadeh-Saffar, E., & Hassani, S.-N. (2023). Rheumatoid arthritis: the old issue, the new therapeutic approach. Stem Cell Research & Therapy. Retrieved from https://stemcellres.biomedcentral.com/articles/10.1186/s13287-023-03473-7
7.Fujii, T., Murata, K., Onizawa, H., Onishi, A., Tanaka, M., Murakami, K., Nishitani, K., Furu, M., Watanabe, R., Hashimoto, M., Ito, H., Fujii, T., Mimori, T., Morinobu, A., & Matsuda, S. (2024). Management and treatment outcomes of rheumatoid arthritis in the era of biologic and targeted synthetic therapies: evaluation of 10-year data from the KURAMA cohort. Arthritis Research & Therapy. Retrieved from https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-023-03251-z
8.Sokka, T., Pincus, T., & Baecklund, E. (2023). Efficacy and safety of Janus kinase inhibitors in patients with rheumatoid arthritis: a systematic review and meta-analysis. Annals of the Rheumatic Diseases. Retrieved from https://ard.bmj.com/content/82/6/791
9.Zhang, X., & Shi, L. (2023). Role of gut microbiota in rheumatoid arthritis pathogenesis: a review. Current Opinion in Rheumatology. Retrieved from https://journals.lww.com/corrheum/Abstract/2023/07000/Role_of_gut_microbiota_in_rheumatoid_arthritis.9.aspx
10.Sidikov A. A., Jo’rayev M. M. SURUNKALI NOINFEKTSION KASALLIKLAR VA XAVFLI OMILLARI KELIB CHIQISHIDA KO’CHA TAOMLARINING O’RNI //SO ‘NGI ILMIY TADQIQOTLAR NAZARIYASI. – 2024. – Т. 7. – №. 6. – С. 201-205.
11.Williams, A. E., Ko, M., & Mahadevan, S. (2023). Economic burden of rheumatoid arthritis in the United States: a systematic review. Rheumatology International. Retrieved from https://link.springer.com/article/10.1007/s00296-023-05028-w
Smith, M. D., & Scott, D. L. (2024). Early diagnosis and treatment in rheumatoid arthritis: the key to better outcomes. The Lancet Rheumatology. Retrieved from https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(24)00045-9/fulltext
