RESPIRATOR DISSTRES SINDROMINI KELIB CHIQISH VA O'LIM SABABLARI, ORGANLARDAGI MORFOLOGIK HAMDA PATOMORFOLOGIK O'ZGARISHLAR
Central Asian Medical University “ Patologiya asoslari va sud tibbiyoti” kafedrasi Phd Nasirdinov Mavlonjon taqrizi ostida
Keywords:
Respirator distress sindromi (ARDS), o'pka shikastlanishi, morfologik o'zgarishlar, patomorfologik o'zgarishlar, o'lim sabablari, alveolar shikastlanish, ekzudat, fibroz, kardiovaskulyar yetishmovchilik, infeksiyalar, jarohatlar, toksik moddalarning ta'siri, klinik natijalar.Abstract
Ushbu maqola respirator distress sindromi (ARDS) ning kelib chiqishi, o'lim sabablari va organlardagi morfologik hamda patomorfologik o'zgarishlari haqida batafsil ma'lumot beradi. ARDS – bu o'pka alveollarining shikastlanishi va ularning funktsional faoliyatining pasayishi bilan tavsiflangan og'ir holat bo'lib, bu holat tez-tez hayotga tahdid soluvchi asoratlarga olib keladi. Maqola infeksiya, jarohatlar va toksik moddalarning o'pka shikastlanishidagi rolini tahlil qiladi, shuningdek bemorlarning muayyan holatlardagi o'lim sabablari, jumladan, o'pka funksiyasidagi keskin pasayish va kardiovaskulyar yetishmovchilik haqida ma'lumot beradi. Morfologik va patomorfologik o'zgarishlar, jumladan, alveolarda suv va ekzudat to'planishi, fibroz o'zgarishlari va kapillyarlarning shikastlanishi hamda ushbu o'zgarishlarning klinik natijalar asociyatsiyasini ko'rib chiqamiz. Ushbu tadqiqot ARDS bilan bog'liq muammolarni tushunishga va ushbu kasallikni erta aniqlash va davolash uchun yangi yondashuvlarni ishlab chiqishga yordam beradi.
References
1.Bernard, G. R., et al. (1994). "The American-European Consensus Conference on ARDS: Definitions, Mechanisms, Relevant Outcomes, and Clinical Trials." American Journal of Respiratory and Critical Care Medicine.
2.Ranieri, V. M., et al. (2012). "Acute respiratory distress syndrome: the Berlin definition." JAMA.
4.Matthay, M. A., et al. (2012). "Acute lung injury and the acute respiratory distress syndrome: a clinical review." The Lancet.
5.Ashbaugh, D.G., et al. (1967). Acute Respiratory Distress in Adults. The Lancet, 2(7511), 319-323.
6.Matthay, M.A., & Zemans, R.L. (2011). The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment. Annual Review of Pathology: Mechanisms of Disease, 6, 147-163.
7.Ranieri, V.M., et al. (2012). Acute Respiratory Distress Syndrome: The Berlin Definition. JAMA, 307(23), 2526-2533.
8.Bernard, G.R., & Artigas, A. (1994). The American-European Consensus Conference on ARDS: Definitions, Mechanisms, Relevant Outcomes, and Clinical Trials. American Journal of Respiratory and Critical Care Medicine, 149(3), 818-824.
9.Ware, L.B., & Matthay, M.A. (2000). The Acute Respiratory Distress Syndrome. New England Journal of Medicine, 342(18), 1334-1349.
10.Hellyer, J.A., et al. (2016). Pathogenesis of Acute Respiratory Distress Syndrome: New Insights. Respiratory Research, 17(1), 146.
11.Zhang, Z., et al. (2020). The Role of Inflammasomes in the Pathogenesis of Acute Respiratory Distress Syndrome. Critical Care, 24(1), 25.
12.Laffey, J.G., & Kavanagh, B.P. (2002). Hypoxemia and Acute Respiratory Distress Syndrome; Pathophysiology and Therapy. Critical Care Medicine, 30(3), S218-S228.
13.Gattinoni, L., et al. (2016). COVID-19: A new challenge for critical care medicine. Critical Care, 24(1), 200.
