CARDIOVASCULAR DISEASE AND INFLAMMATION

Abstract

 The study reviewed research on the function of endothelium local factors, including the build-up of smooth muscle cells, T and B lymphocytes, macrophages, matrix metalloproteinase (MMP), and high-sensitivity C-reactive protein (CRP). In coronary artery disease (CAD), oxidized low-density lipoprotein (OLDL) and CRP are directly linked to inflammatory arterial damage. One of the leading causes of death and disability in developed nations is coronary heart disease (CHD). Although numerous risk factors for the onset and progression of CHD have been investigated, the primary cause and trigger for acute coronary problems remain unclear. Atherosclerosis and thrombosis are the primary processes that cause acute coronary syndrome (ACS) [1]. The so-called susceptible atherosclerotic plaques are typically the target of inflammation. Endothelial cells, SMC, monocytes, neutrophils, platelets, macrophages, T-lymphocytes, and B-lymphocytes are the primary active constituents of loose connective tissue.