SOME ASPECTS OF GENETIC PROGNOSTIC FACTORS FOR THE COURSE OF NONSPECIFIC ULCERATIVE COLITIS
Keywords:
nonspecific ulcerative colitis, tumor necrosis factor alpha, gene polymorphism, steroids., zAbstract
An open case-control study involving 61 patients with ulcerative colitis examined the effect of the TNFα G-308A gene polymorphism on the prognosis of ulcerative colitis, the effectiveness of steroid therapy, and the formation of the need for cytostatic therapy.
References
Valuyskikh E.Yu. and others. Clinical and genetic aspects of inflammatory bowel diseases // Russian Journal of Gastroenterology, Hepatology, Coloproctology. - 2018. - T. 18, No. 6. - P. 68-74.
Konenkov V.I., Smolnikova M.V. Structural basis and functional significance of allelic polymorphism of human cytokine genes and their receptors // Medical Immunology. - 2013. - T. 5, No. 1-2. — P. 11-28.
Nonspecific inflammatory bowel diseases / Ed. G. I. Vorobyova, I. L. Khalifa. - M.: Miklos, 2018. - 399 p.
Samokhodskaya L.M., Ignatova T.M., Abdullaev S.M., Krasnova T.N., Nekrasova T.P., Mukhin N.A., Tkachuk V.A. Prognostic value of the combination of allelic variants of cytokine genes and hemochromatosis in patients with chronic hepatitis C // RZHGGK. - 2017. - T. 2. - P. 50-56.