DIAGNOSIS OF UTERINE MYOMA BY USING BIOLOGICAL MARKERS

Authors

  • Akhmedova N.M., Mutalipova Madinabonu Xamidjon qizi Andijan State Medical Institute,Uzbekistan Author

Keywords:

uterine myoma, biological markers, CA-125, glycodelin, vascular endothelial factor, reproductive age, premenopause.

Abstract

Uterine myoma and the complications it causes in women remain not fully studied and are increasing, despite the advances in modern medicine. It is emphasized that uterine myoma is the most common gynecological disease over the past 5 years, and in women of reproductive age, this disease can also lead to infertility. In premenopausal women, uterine myoma can lead to heavy or prolonged menstrual bleeding, severe pelvic pain, and in severe cases, urinary incontinence. Our research aims to highlight the role of biological markers, such as CA-125, glycodelin, and vascular endothelial factor, in the early diagnosis of uterine myoma in women of any age. Early diagnosis and identification of these markers can help prevent the development of complications associated with uterine myoma.The study focuses on exploring the potential of these biological markers as tools for early detection and monitoring of uterine myoma. By understanding the relationship between the levels of these markers and the presence, severity, and progression of uterine myoma, healthcare providers can optimize diagnostic and treatment strategies, leading to improved patient outcomes. The findings of this research are expected to contribute to the advancement of knowledge in the field of gynecology, particularly in the area of uterine myoma management. The early identification of uterine myoma using reliable biomarkers can facilitate timely intervention, reduce the burden of complications, and enhance the overall quality of life for affected women.

References

1.Sharma, S., et al. (2017). "CA-125 Levels and Uterine Fibroids: A Correlation Study." Gynecologic Oncology.

2.Akhmedov, A. T., et al. (2019). "The Role of Glycodelin in Uterine Fibroids." Journal of Clinical Endocrinology & Metabolism.

3.Sullivan, M. H., et al. (2020). "Vascular Endothelial Growth Factor and Uterine Fibroids: Implications for Pathogenesis." The American Journal of Pathology.

4.dr Dutta's: Gynecology (2022) 540 p

5.Woodward/ Kennedy Sohaey: diagnostic imaging in gynecology. 348p

6."Biomarkers in Gynecological Cancer: Methods and Protocols" edited by Anirban Mitra

7."Biomarkers in Reproductive Medicine" edited by David Baird and Siladitya Bhattacharya

8."Gynecologic Oncology Handbook: An Evidence-Based Clinical Guide" by Megan Hosey and Sachin Apte

9."Uterine Fibroids: Pathogenesis and Management" edited by James H. Segars and Cassing Hammond

10."Gynecology" by Sabaratnam Arulkumaran, Aris Papageorghiou, and Frank Chervenak

Published

2025-03-11