THE ROLE OF ADDITIVES AND PRESERVATIVES IN ENSURING THE QUALITY OF SYRUP DOSAGE FORMS
Keywords:
Additives, preservatives, syrup dosage forms, stability, microbial contamination, flavorings, colorants, sweeteners, regulatory standards, shelf life.Abstract
This article examines the critical functions of additives and preservatives in maintaining the quality of syrup dosage forms. Additives such as sweeteners, flavorings, and colorants enhance the organoleptic properties of syrups, improving patient compliance by making them more palatable and visually appealing. Preservatives, on the other hand, are essential for preventing microbial contamination and extending the shelf life of syrup formulations. The article details various types of preservatives, their mechanisms of action, and their impact on syrup stability and safety. It also covers regulatory standards governing their use to ensure that syrups remain effective and safe for consumption.
References
Badam L, Bedekar S.S., Sonawane K.B. and Joshi S.P. (2002), “ Ivitro antiviral activity of Bael (Aegle marmelos Corr.) upon human Cox sackiviruses B1-B6, j. Commun Dis, 34 Page No.88.
Purohit S. S and Vyas S. P, “In: Aegle marmelos Correa ex Roxb,(Bael), Medicinal plant cultivation- A scientific approach”, Agrobios, Jodhpur, 2004. P.P.498-504
Maity P., Hansda D., Bandyopadhyay U. & Mishra D.K., (2009) “Biological activities of crude extracts of chemical constituents of Bael, Aegle marmelos (L.) Corr.” Indian Journal of Experimental Biology, Vol 47, p.p. 849-861
Kar A. Choudhry B. K. and Bandhopadhyay N. G. (2003), “Comparative evaluation of hypoglycemic activity of some Indian medicinal plants in alloxan diabetic rats” J Ethnopharmacol. 84, Page No.105-108.
Lampronti I, Martello D., Bianchi N., Borgatti M., Lambrtini E.,. Piva R, Jabbars S., Choudhuri M. S., Khan M. T. and Gambari R. (2003), “In Vitro antiproliferative effect on human tumor cell lines of extracts from the bangladesi medicinal plant Aegle marmelos Correa.” Phytomedicine, 10, Page No. 300-308.
